Health Studies

The Flat-Coated Retriever Foundation has supported various health studies over the years. Below is a listing of those studies and the differing levels of support. Click on the study for more detailed information.

If you would like to see the studies marked "closed" as well, click here.

Detail:

Click for details

Project Status:

Date Approved:

2012-07-06

Amount:

-$5,000.00

Researcher:

Dr. Carl Walkley - St Vincent's Institute of Medical Research

Description:

Defining New Therapeutic Approaches for Osteosarcoma through Genome Wide Screening and Comparative Oncology

For More Information:

Detail:

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Project Status:

open

Date Approved:

11/09/2005

Amount:

$9,400.00

Researcher:

FCRSA

Description:

Flat-coated Retriever health database project

For More Information:

Detail:

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Project Status:

open

Date Approved:

12/19/2005

Amount:

$5,000.00

Researcher:

Breen - North Carolina State University

Description:

Heritable and Sporadic Genetic Lesions in Canine Lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

01/30/2006

Amount:

$1,700.00

Researcher:

Kisseberth - Ohio State University

Description:

MicroRNAs and Canine Lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

3/21/2006

Amount:

$1,000.00

Researcher:

Description:

Financial support for AHT blood collection

For More Information:

Detail:

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Project Status:

open

Date Approved:

3/21/2006

Amount:

$5,000.00

Researcher:

Dr. Kerstin Lindblad-Toh, Dr. Chieko Azuma - Broad Institute/Tufts University

Description:

Mapping Genes Associated with Canine Hemangiosarcom

For More Information:

Detail:

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Project Status:

open

Date Approved:

12/15/2006

Amount:

$1,000.00

Researcher:

Ted Valli, DVM - University of Illinois

Description:

A Collaborative Study by Veterinary Oncologists, Pathologists abd Diagnostic Laboratories to enhance the detection diagnosis and treatement of canine Lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

12/15/2006

Amount:

$2,500.00

Researcher:

William Kisseberth - Ohio State University

Description:

MicroRNA Profiling and MicroRNA-Based Treatment of Canine Cancers

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Detail:

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Project Status:

open

Date Approved:

2008-05-09

Amount:

$5,000.00

Researcher:

Matthew Breen PhD - North Carolina State University

Description:

The Prognostic Significance of Chromosome Aneuploidy in Canine Lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-05-09

Amount:

$5,000.00

Researcher:

Matthew Breen PhD & Jaime Modiano VMD PhD - North Carolina State University/University of Minnesota

Description:

Heritable and Sporadic Genetic Lesions in Canine Osteosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-05-09

Amount:

$3,000.00

Researcher:

Cheryl London DMV, PhD - Ohio State University

Description:

Investigating the Role of STAT3 Activation on Canine Osteosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-05-09

Amount:

$20,000.00

Researcher:

Elaine Ostrander PhD, Catherine Andre PhD - NHGRI/NIH & CNRS

Description:

Positional Cloning of Two Genes for Malignant Histiocytosis(MH) in the Bernese Mountain Dog

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-05-09

Amount:

$3,000.00

Researcher:

Cheryl London DMV, PhD - Ohio State University

Description:

Characterization and Modulation of Canine Mast Cell Derived Eicosanoids

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-05-09

Amount:

$20,000.00

Researcher:

Jaime Modiano VMD PhD - University of Colorado

Description:

Innovative Molecular Targets for Prevention and Treatment of Canine Hemangiosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-12-18

Amount:

$5,000.00

Researcher:

Nicola Mason, BVetMed, DACVIM, PhD - University of Pennsylvania

Description:

Immune Targeting of Canine Hemangiosarcoma Using a Canine Derived Single Chain Antibody Approach

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-12-18

Amount:

$2,500.00

Researcher:

Chieko Azuma, DVM, PhD, DACVR - Tufts University

Description:

Identifying Mutations in Genes Associated with Canine Hemangiosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-12-18

Amount:

$5,000.00

Researcher:

Timothy D. O'Brien DVM, PhD - University of Minnesota

Description:

Canine Non-Hodgkin Lymphoma: Characterization and Prognostic Value of Cancer Stem Cells

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-12-18

Amount:

$2,500.00

Researcher:

Steven W. Dow, DVM, PhD - Colorado State University

Description:

Liposomal BisphosphonateTherapy for Malignant Histiocytosis

For More Information:

Detail:

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Project Status:

open

Date Approved:

2008-12-18

Amount:

$2,500.00

Researcher:

Susan E. Lana, DVM, DACVIM - Colorado State University

Description:

Measurement of Minimal Residual Disease Using Real Time PCR in Canine Lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2009-10-21

Amount:

$10,000.00

Researcher:

Dr. Steven W. Dow, DVM PhD - Colorado State University

Description:

Liposomal Bisphophonate Therapy for Malignant Histiocytosis

For More Information:

Detail:

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Project Status:

open

Date Approved:

2009-10-21

Amount:

$500.00

Researcher:

Dr. Kimberly A. Selting, D.V.M. - University of Missouri

Description:

Comparison of Percentage of T Regulatory Cells in Dogs with Spontaneously Occurring Lymphoma Following Oral versus Intravenous Cyclophosphamide

For More Information:

Detail:

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Project Status:

open

Date Approved:

2009-10-21

Amount:

$500.00

Researcher:

Dr. Kimberly Weber, D.V.M. - University of Illinois

Description:

Expression of Vascular Endothelial Markers in Canine Hemangiosarcoma and Their Use in Diagnostic Cytology Using Immunocytochemistry

For More Information:

Detail:

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Project Status:

open

Date Approved:

2009-10-21

Amount:

$2,500.00

Researcher:

Dr. Don Bellgrau, Ph.D. - ApopLogic Pharmaceuticals, LLC

Description:

Evaluation of Efficacy of Fasaret in Dogs with Osteosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2009-10-21

Amount:

$500.00

Researcher:

Dr. Cristina Gobello, DVM - National University of La Plata

Description:

Grant 01241-A: Detection of DNA Damage in Response to Cooling Storage in Canine Spermatozoa Using Single-Cell Gel Electrophoresis (Comet Assay)

For More Information:

Detail:

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Project Status:

open

Date Approved:

2009-10-21

Amount:

$10,000.00

Researcher:

Jaime Modiano VMD PhD - University of Colorado

Description:

Innovative Molecular Targets for Prevention and Treatment of Canine Hemangiosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2009-10-21

Amount:

$10,000.00

Researcher:

Dr. Michael Kent - University of California, Davis

Description:

Grant No. DK06CA-005 | Treatment of canine lymphoma with liposome encapsulated doxorubicin bound to a high affinity ligand

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-03-08

Amount:

$3,000.00

Researcher:

Dr. Kelly D. Mitchell - University of Guelph, Canada

Description:

Clinical Trial of IMHA Treatments

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-03-08

Amount:

$3,000.00

Researcher:

Dr. Tracy Stokol - Cornell University

Description:

Determining causes of abnormal clotting

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-03-08

Amount:

$3,000.00

Researcher:

Dr. Cheryl London - Ohio State University

Description:

Studying how mast cells become malignant

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-03-08

Amount:

$3,000.00

Researcher:

Dr. Timothy M. Fan - University of Illinois

Description:

Targeted delivery of chemotherapy to fight bone cancer

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-03-08

Amount:

$2,500.00

Researcher:

Kerstin Lindblad-Toh, PhD - Broad Institute

Description:

Mutation detection and functional analysis of multiple loci for osteosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-03-08

Amount:

$2,500.00

Researcher:

Steven Dow DVM PhD - Colorado State University

Description:

Lipsomal Bisphosphonate Therapy for Malignant Histiocytosis

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$25,000.00

Researcher:

Dr. Elaine Ostrander, PhD - National Human Genome Research Institute

Description:

Positional Cloning of Histiocytic Sarcoma (HS) in the Bernese Mountain Dog (BMD) and Flat Coated Retriever (Part A - See also 01410B)

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$10,000.00

Researcher:

Dr. Jaime F Modiano, VMD PhD - University of Minnesota

Description:

Mechanistic Relationship of IL-8 in Cell Proliferation and Survival of Canine Hemangiosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$2,500.00

Researcher:

Dr. Steven W. Dow, DVM PhD - Colorado State University

Description:

Treatment with Liposomal Clodronate to Restore Tumor Sensitivity to Chemotherapy in Malignant Histiocytosis

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$2,500.00

Researcher:

Dr. Nicola J Mason, BVetMed, PhD - University of Pennsylvania

Description:

Identification and Characterization of a Canine Derived Single Chain Antibody that Binds and Neutralizes Canine VEGF

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$2,000.00

Researcher:

Julie Ellerhorst

Description:

Targetting iNOS in Canine Oral Melanoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$2,000.00

Researcher:

Dr. Douglas H Thamm, VMD - Colorado State University

Description:

c-Kit Mutation and Localization Status as Response Predictors in Canine Mast Cell Tumors Treated with Toceranib or Vinblastine: A Response-Adaptive Randomized Trial

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$10,000.00

Researcher:

Drs. Jaime F. Modiano, Matthew Breen and Kerstin Lindblad-Toh - North Carolina State University, University of Minnesota and Uppsala University, Sweden

Description:

MADGiC: Making Advanced Discoveries in Golden Cancers

For More Information:

Detail:

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Project Status:

open

Date Approved:

2010-12-09

Amount:

$3,000.00

Researcher:

Dr Cheryl London - Ohio State University

Description:

Studying how mast cell tumors become malignant

For More Information:

Detail:

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Project Status:

open

Date Approved:

2011-08-30

Amount:

$10,000.00

Researcher:

Drs. Jaime F. Modiano, Matthew Breen and Kerstin Lindblad-Toh - North Carolina State University, University of Minnesota and Uppsala University, Sweden

Description:

MADGiC: Making Advanced Discoveries in Golden Cancers

For More Information:

Detail:

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Project Status:

open

Date Approved:

2011-08-30

Amount:

$3,000.00

Researcher:

Dr Cheryl London - Ohio State University

Description:

Studying how mast cell tumors become malignant

For More Information:

Detail:

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Project Status:

open

Date Approved:

2011-08-30

Amount:

$5,000.00

Researcher:

Dr. Barbara Biller

Description:

Evaluating a novel drug for lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2011-12-27

Amount:

$10,000.00

Researcher:

Dr. Matthew Breen, PhD - North Carolina State University

Description:

High-Resolution Cytogenetic Analysis of Histiocytic Malignancies and Development of a Targeted Assay to Screen for Expression Level Changes

For More Information:

Detail:

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Project Status:

open

Date Approved:

2011-12-27

Amount:

$5,000.00

Researcher:

Dr. Carl Walkley - St Vincent's Institute of Medical Research

Description:

Defining New Therapeutic Approaches for Osteosarcoma through Genome Wide Screening and Comparative Oncology

For More Information:

Detail:

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Project Status:

open

Date Approved:

2011-12-27

Amount:

$2,500.00

Researcher:

Dr. Douglas H Thamm, VMD - Colorado State University

Description:

Evaluation of GS-9219 in Canine Cutaneous Lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2011-12-27

Amount:

$2,500.00

Researcher:

Dr. Stephen A Johnston, PhD - Arizona State University

Description:

Serum Antibody Reactivity Profiling for Canine Lymphoma Detection and Monitoring

For More Information:

Detail:

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Project Status:

open

Date Approved:

2012-11-27

Amount:

$10,000.00

Researcher:

Dr Jaime Modiano VMD PhD - University of Minnesota

Description:

Targeting Multipotency to Arrest Hemangiosarcoma Progression and Improve Outcomes

For More Information:

Detail:

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Project Status:

open

Date Approved:

2012-11-27

Amount:

$2,500.00

Researcher:

Dr. Nicola J Mason, BVetMed, PhD - University of Pennsylvania

Description:

Clinical advancement of RNA-transfected CD40-B cell vaccine technology for cancer therapy

For More Information:

Detail:

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Project Status:

open

Date Approved:

2012-11-27

Amount:

$2,500.00

Researcher:

Dr. Bruce F Smith, VMD PhD - Auburn University

Description:

Evaluation of a conditionally replicative adenoviral vector for the treatment of canine osteosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2012-11-27

Amount:

$5,000.00

Researcher:

Description:

CHF committed funding to support various research projects around Bloat

For More Information:

Detail:

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Project Status:

open

Date Approved:

2012-11-27

Amount:

$1,000.00

Researcher:

Dr. Kerstin Lindblad-Toh, PhD - Broad Institute

Description:

Identifying disease related genes in renal dysplasia in Boxers and additional breeds.

For More Information:

Detail:

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Project Status:

open

Date Approved:

2013-02-15

Amount:

$5,000.00

Researcher:

Dr Dawn L Duval - Colorado State University

Description:

Identifying bone cancer response to treatment

For More Information:

Detail:

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Project Status:

open

Date Approved:

2013-02-15

Amount:

$5,000.00

Researcher:

Dr Daniel Gustafson - Colorado State University

Description:

Developing ways to improve cancer treatement

For More Information:

Detail:

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Project Status:

open

Date Approved:

2013-02-15

Amount:

$5,000.00

Researcher:

Dr Cheryl London - The Ohio State University

Description:

Studying how mast cell tumors spread

For More Information:

Detail:

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Project Status:

open

Date Approved:

2013-02-15

Amount:

$5,000.00

Researcher:

Dr Erin B. Dickerson - University of Minnesota

Description:

Assessing how a protein helps hemangiosarcoma cells survive

For More Information:

Detail:

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Project Status:

open

Date Approved:

2014-06-20

Amount:

$3,000.00

Researcher:

Dr Amy LeBlanc - University of Tennessee

Description:

Exploring the use of a virus-based anticancer strategy for lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2014-06-20

Amount:

$3,000.00

Researcher:

Dr Tomothy Fan - University of Illinois

Description:

Assessing immune stimulation as a potential therapy for osteosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2014-06-20

Amount:

$5,000.00

Researcher:

Dr Erin Dickerson - University of Minnesota

Description:

Testing strategies to treat drug-resistant hemangiosarcomas

For More Information:

Detail:

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Project Status:

open

Date Approved:

2014-06-20

Amount:

$5,000.00

Researcher:

Dr Matthew Breen - North Carolina State University

Description:

Developing a way to predict length of disease-free intervals for dogs with bone cancer

For More Information:

Detail:

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Project Status:

open

Date Approved:

2014-06-20

Amount:

$3,000.00

Researcher:

Dr Cheryl London - Ohio State University

Description:

Determining how overexpression of miR-9 helps osteosarcoma spread

For More Information:

Detail:

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Project Status:

open

Date Approved:

2014-12-23

Amount:

$5,000.00

Researcher:

Dr Timothy J Stein - University of Wisconsin, Madison

Description:

Defining the role of Frizzled-6 in Osteosarcoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2014-12-23

Amount:

$1,000.00

Researcher:

Dr Allen R Chen - John Hopkins University

Description:

Animal Assistance Therapy: Ensuring animal health and program sustainability in the context of hospital-associated infections

For More Information:

Detail:

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Project Status:

open

Date Approved:

2015-05-22

Amount:

$10,000.00

Researcher:

Modiano, Breen & Lindblad-Toh - University of Minnesota, North Carolina State University and the Broad Institute

Description:

Innovations in Prevention, Diagnosis and Treatment of Cancer

For More Information:

Detail:

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Project Status:

open

Date Approved:

2015-12-29

Amount:

$10,000.00

Researcher:

Matthew Breen, PhD - North Carolina State university

Description:

Determining the prognostic value of identifying genetic mutations in dogs with lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2015-12-29

Amount:

$10,000.00

Researcher:

Paul R. Hess, DVM, PhD - North Carolina State university

Description:

Measuring chemotherapy drug resistance in dogs with T-cell lymphoma

For More Information:

Detail:

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Project Status:

open

Date Approved:

2015-12-29

Amount:

$10,000.00

Researcher:

Daniel L. Gustafson, PhD - Colorado State University

Description:

Predicting chemotherapy drug response for dogs with bone cancer

For More Information:

Detail:

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Project Status:

open

Date Approved:

2016-12-16

Amount:

$10,000.00

Researcher:

Dr Matthew Breen - North Carolina State University

Description:

Finding new therapy targets for Mast Cell Tumors

For More Information: